SpectraDx
pectraDx
light to insight
SpectraDxlight to insight
Raman Spectroscopy

Raman Diagnostic Software

Integrate Horiba, Renishaw, and Thermo Fisher Raman spectrometers into clinical diagnostic workflows. SpectraDx delivers instrument automation, spectral classification, and seamless EHR integration for Raman-based diagnostics.

Overview

What is Raman in Clinical Diagnostics?

Raman spectroscopy works by shining a laser — typically green at 532 nm — at a sample and measuring the scattered light. Most photons scatter elastically at the same energy, but a small fraction scatter inelastically, shifted by an amount that corresponds to specific molecular vibrations. This Raman shift creates a molecular fingerprint complementary to FTIR and often more specific.

Clinically, Raman has distinct advantages: it works through water (unlike FTIR), requires minimal sample preparation, and can analyze samples through glass or plastic containers. These properties make it ideal for point-of-care applications — bacterial identification directly from clinical specimens, real-time drug identification in emergency departments, and intraoperative tissue assessment during surgery.

The instrumentation is mature. What's missing is the software layer that transforms Raman measurements into clinical actions — patient association, quality control, ML-based classification, and structured reporting to hospital information systems.

Clinical Applications

Bacterial ID & AST

Identify pathogens and predict antibiotic resistance in under 90 minutes — versus 24–72 hours for culture

Surgical Margin Assessment

Real-time tissue classification during surgery using stimulated Raman histology (SRH)

Drug Identification

Identify unknown substances including fentanyl analogs through sealed packaging in the ED

SERS Diagnostics

Surface-enhanced Raman for ultra-sensitive point-of-care detection of biomarkers and pathogens

Instruments

Supported Instruments

SpectraDx provides modular instrument adapters. Each adapter handles vendor-specific protocols so your clinical workflow stays consistent.

Horiba

LabRAM

LabSpec SDK integration for confocal Raman mapping, point measurements, and automated spectral acquisition.

In Development

Horiba

XploRA Plus

Compact research-grade Raman with motorized stage and LabSpec automation interface.

Planned

Renishaw

inVia Qontor

WiRE software integration for high-performance confocal Raman with LiveTrack focus tracking.

Planned

Renishaw

Virsa

Fiber-optic coupled Raman analyzer designed for remote and clinical sampling applications.

Planned

Thermo Fisher

DXR3

OMNIC integration for the DXR3 Smart Raman with automated alignment and fluorescence correction.

Planned

Forward Edge AI

Blaise

Handheld Raman with built-in ML classification and cloud connectivity for field and clinical use.

In Development

The Problem

The Software Gap

Instrument vendor software like LabSpec (Horiba), WiRE (Renishaw), OMNIC (Thermo Fisher) is designed for research, not clinical deployment.

What vendor software provides

Spectral acquisition and measurement
Data visualization and analysis
Library search and matching
File export and format conversion

What clinical deployment requires

Patient identification and workflow
HL7/FHIR integration with LIS/EHR
Billing codes and reimbursement
Multi-site deployment and management
Clinician-friendly result interface
Regulatory audit trail (21 CFR Part 11)
Multi-vendor instrument support

Platform

How SpectraDx Works with Raman

01

Instrument Automation

Programmable measurement sequences for Horiba and Renishaw spectrometers. Automated laser power, exposure time, and accumulation settings for consistent clinical results.

Learn more →
02

Spectral Classification

Deploy ML models trained on Raman spectra for bacterial identification, tissue classification, and substance identification with calibrated confidence scores.

Learn more →
03

Clinical Integration

Route Raman diagnostic results through HL7v2 or FHIR R4 to your LIS/EHR. Support for LOINC observation codes and CPT billing.

Learn more →
04

SERS Support

Process surface-enhanced Raman spectra from nanostructured substrates for high-sensitivity point-of-care diagnostic applications.

Learn more →

Deploy Raman-based diagnostics with SpectraDx

From Raman spectra to clinical results in your EHR. Bacterial ID, drug testing, and surgical guidance — one platform.